There is a launch of norepinephrine from your descending inhibitory bulbospinal neurons that binds to alpha-two-receptors in the dorsal horn to minimize afferent agony transmission and make analgesia. Hence, drugs like clonidine that target alpha-2 receptors can impact the transmission of pain. Clonidine is dispersed in breast milk; caution https://vonc047lke9.wikimidpoint.com/user