This refers to how an allosteric modulator affects signaling for a certain orthosteric agonist. Such as, an allosteric modulator could change THC signaling, but not endogenous cannabinoid signaling. A significant possible endogenous damaging allosteric modulator for CB1 is definitely the steroid hormone, pregnenolone [forty–forty two]. Some (while not all [43–forty https://marioqbksy.blog-a-story.com/13396086/examine-this-report-on-cannabis-strains